EBV Associated Lymphomatoid Granulomatosis in 18-Year-Old Male: A Case Report

EBV Associated Lymphomatoid Granulomatosis in 18-Year-Old Male: A Case Report

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Lymphomatoid granulomatosis (LYG) is an Epstein-Barr virus (EBV)-associated lymphoproliferative disease.It is considered a rare entity in pediatric patients.An adolescent male with lobar consolidation suspected of having pneumonia was resistant to antibiotics and had persistently abnormal radiographs with chest pain.The patient was diagnosed with pulmonary LYG through video-assisted thoracoscopic dorisvale station for sale surgery (VATS) lung biopsy.He received eight cycles of rituximab, vincristine, cyclophosphamide, and prednisolone (R-CVP) but had progressive disease.

As the patient developed hypogammaglobulinemia after eight courses of rituximab, he received intravenous gamma globulin (IVIG) at regular interval.With immune augmentation effect of IVIG and immune modulation treatment with prednisolone, the patient has shown no aggravation of the lung lesions.Considering its rarity, high mortality, and frequent mel axolotl relapses, diagnostic methods investigating the radiologic abnormalities can help in early treatment initiation.